WebThe COSMIC website notes an up-regulated expression score for ZC2 in diverse human cancers of 501, which is 1.1-fold of the average score of 462 for the human protein kinases. The down-regulated expression score of 1 for this protein kinase in human cancers was 98% lower than average score of 60 for the human protein kinases. WebSep 1, 2008 · We designed hybrid structures of Dasatinib and the previously known EPHA2 binders CHEMBL249097, PD-173955 and a known EPHB4 inhibitor in order to exploit both the ATP pocket entrance as well as ...
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Web1.Identification Product name: Lck inhibitor 2 Catalog#: 2893DC IUPAC name: 3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide Product use restrictions:Only for research and development use by, or directly under the supervision of, http://www.cipsm.uni-muenchen.de/publications/research-area-e/chemoproteomics-aided-medicinal-chemistry-for-the-discovery-of-epha2-inhibitors/ shape up swimwear
RCSB PDB - 5NKE: Crystal Structure of Ephrin A2 (EphA2) Receptor ...
WebDec 31, 2024 · hybrid structures of Dasatinib and the previously known EPHA2 binders CHEMBL249097, PD-173955 and a known EPHB4 inhibitor in order to exploit both the ATP pocket entrance as well as the ribose pocket as binding epitopes in the kinase EPHA2. Medicinal chemistry and inhibitor design was guided by a WebWe designed hybrid structures of Dasatinib and the previously known EPHA2 binders CHEMBL249097, PD-173955 and a known EPHB4 inhibitor in order to exploit both the … WebDec 31, 2024 · hybrid structures of Dasatinib and the previously known EPHA2 binders CHEMBL249097, PD-173955 and a known EPHB4 inhibitor in order to exploit both the … poodle bottle cover pattern