WebJan 30, 2024 · Introduction. Silencing gene expression, protein-coding or non-coding DNA, is a very important tool to interrogate the function of DNA. It has been reported that, with the guidance of customized single guide RNA, the catalytically inactivated dead Cas9 (dCas9) could bind to targeted promoter region to disrupt the transcriptional initiation and … WebJun 2, 2016 · Chimeric REpressor gene-Silencing Technology (CRES-T) was developed as a specific technology for gene silencing, mainly used for analyzing the function of …
National Center for Biotechnology Information
WebSep 21, 2004 · We have recently developed an effective system for gene silencing using a chimeric repressor (chimeric repressor silencing technology: the CRES-T system). In this system, a transcription factor is converted into a dominant repressor by fusion with the EAR-motif repression domain from SUPERMAN ( Hiratsu et al ., 2003 ). WebCIN-type TCP genes have redundant Chimeric repressor gene-silencing technology (CRES- molecular functions to regulate margin development T) has provided unique transgenic ornamental flowers (Koyama et al. 2007). A chimeric repressor, (Nakatsuka et al. 2011; Shikata et al. 2011; Tanaka et al. TCP3SRDX, which consists of Arabidopsis … flowers easy to grow in florida
CRES-T, an effective gene silencing system utilizing chimeric ...
WebMar 10, 2014 · Arabidopsisplants transformed with a chimeric repressor for 6 transcription factors (TFs), including ADA2b, Msantd, DDF1, DREB26, AtGeBP, and ATHB23, that … WebJan 1, 2016 · A modified version of the EAR domain, called SRDX (LDL DLE LRL GFA), has been used to create chimeric repressor gene silencing technology (CRES-T; Mitsuda et al., 2011). SRDX has the advantage that it is a short amino acid sequence that can be fused to many different transcription factors to obtain a strong repressive form. WebMar 28, 2016 · The chimeric repressor gene silencing technology (CRES-T) system converts a transcriptional activator into a strong repressor by fusion to the SRDX repression domain; this process induces a phenotype similar to loss-of-function alleles ( 27) and can also confer tolerance to various abiotic stresses ( 28 ). flowers easy to grow from seed