High dose cytarabine regimen

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August undefined, 2024

WebCALGB stated that high-dose cytarabine delivered as a bolus infusion of 3000 mg/m 2 every 12 hours on days 1, 3 and 5 (HDAC-135) was superior to a continuous infusion at a dose of 100 or 400 mg/m 2 over five days. r In the pivotal trial of post-remission treatment, the HDAC regimen was given on days 1,3 and 5 to ensure an equivalent 5-day duration … Web6 de abr. de 2016 · Between Feb 19, 2010, and Aug 27, 2014, 227 eligible patients were recruited. 219 of these 227 enrolled patients were assessable. At median follow-up of 30 months (IQR 22–38), patients treated with …

Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus ...

WebFollowing radiation therapy, all patients received two consolidation high-dose cytarabine cycles (each cycle 28 days) comprising cytarabine 3 g/m 2 /day on days 1 and 2 of each cycle. r. The incidence of neurotoxicity related to the combination of WBRT and high dose methotrexate is significantly higher in patients aged greater than 60 years ... Web22 de jan. de 2024 · Ferreri, A. J. et al. High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a … florian wandl

High Dose Cytarabine Therapy - Health Service Executive

WebWe performed a retrospective analysis of an alternative induction regimen using high dose cytarabine (HiDAC) and mitoxantrone (MITO) administered to 78 high-risk patients … Web10 de jul. de 2003 · Main. Cytarabine (cytosine arabinoside) is a powerful antimetabolite used in the treatment of acute myeloid leukaemia (AML). Corneal toxicity from high-dose intravenous cytarabine therapy has been ... WebTraductions en contexte de "specific regimen, or" en anglais-français avec Reverso Context : So regardless of your current health, specific regimen, or potential risk factors you … florian walther jena

High-dose methotrexate-based regimens and post-remission

Oxaliplatin before autologous transplantation in combination with high …

Web17 de mai. de 2024 · One regimen consisted of four drugs that incorporated high-dose cytarabine plus HD-MTX, procarbazine, and vincristine. The second regimen consisted of two drugs, HD-MTX and temozolomide, and did not include high-dose cytarabine. In each of these studies, the regimen that contained high-dose cytarabine was associated with … WebHiDAC: In general, patients may receive the HiDAC regimen (high dose cytarabine) in the salvage setting if they have not received it previously for induction either with or without … great team building activities dfwWeb27 de jan. de 2024 · Hyper CVAD high-dose Methotrexate/ Cytarabine (with Cytarabine dose reduced to 1,000mg/m 2) 10,11,40 Cycle A: Days 1-3: Cyclophosphamide 300mg/m 2 IV over 3 hours every 12 hours for 6 doses f great team backgrounds

"Web22 de jun. de 2010 · Overall response rates ranging from 55% to 67%, including CR rates ranging from 15% to 31%, have been previously reported with dexamethasone, cytarabine, and cisplatin in patients with NHL … " - High dose cytarabine regimen

High dose cytarabine regimen

Web31 de out. de 2009 · Background: Chemotherapy with high-dose methotrexate is the conventional approach to treat primary CNS lymphomas, but superiority of … Web16 de jun. de 2024 · Cytarabine based induction/consolidation regimen may be combined with ... Edwards CG, Arthur DC, et al. Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid ...

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WebConclusion: Our results suggest that a high dose of IDA (12 mg/m2) combined with cytarabine is a suitable and safe initial remission induction regimen that results in … WebPhase II study of a salvage regimen using cyclophosphamide, high-dose cytarabine, dexamethasone, etoposide, and rituximab in patients with relapsed or refractory B-cell …

WebLarger studies are required to establish the therapeutic potential of the regimen. ... Dexamethasone, high-dose cytarabine, and oxaliplatin (DHAOx) as salvage treatment … WebGrade 3-4 cytopenias are expected with this regimen. Delay treatment if neutrophils < 1.0 9x 10 /L and/or platelets < 100 x 109/L until count recovery. Renal impairment Discuss with consultant as some circumstances may warrant 100% dose. CrCl (mL/min) Methotrexate dose Cytarabine dose ≥ 80 100% 100% 60-79 65% 45-59 50% 60% 30-44 50% 50%

WebGrade 3-4 cytopenias are expected with this regimen. Delay treatment if neutrophils < 1.0 9x 10 /L and/or platelets < 100 x 109/L until count recovery. Renal impairment Discuss … http://www.druglib.com/druginfo/cytarabine/indications_dosage/

WebHiDAC: In general, patients may receive the HiDAC regimen (high dose cytarabine) in the salvage setting if they have not received it previously for induction either with or without an anthracycline. An exception can be made in patients who suffer a late relapse more than 18 months from their initial CR, as they may achieve a second CR by retreatment with …

Web15 de abr. de 2024 · Subsequently, she achieved complete response to R-MPV regimen and was further started on reduced dose of whole-brain radiotherapy (WBRT). Further, … florian wanner anwaltWeb1 de fev. de 2024 · Condition: Refractory/Relapse Acute Myeloid Leukemia; Intervention: Intervention Type: Drug Intervention Name: Venetoclax Description: VA regimen Drug: Venetoclax orally once daily (100 mg d1, 200 mg d2, 400 mg d3-21); Drug: Azacitidine 75 mg/m2 subcutaneously once daily on days 1-7. CAG regimen Drug: Cytarabine … great team building activities for meetingsWebIn this prospective study, we examined the toxicity and efficacy of an intensified conditioning regimen for treatment of patients with relapsed or high-risk acute lymphoblastic leukemia who undergo allogeneic hematopoietic stem cell transplantation. Fifteen patients received fludarabine 30 mg/m(2), … great team buildingWebConclusion: Our results suggest that a high dose of IDA (12 mg/m2) combined with cytarabine is a suitable and safe initial remission induction regimen that results in superior long-term survival of adult AML patients, particularly patients in … florian wanner radio 24WebCycle 2 and 4 (High dose cytarabine plus rituximab) – this will be set as an inpatient regimen in Aria Drug Dose Days Administration Cytarabine 3000mg/m 2 every 12 hours 1 and 2 (4 doses) Intravenous infusion in 1000ml sodium chloride 0.9% over 180 minutes Rituximab 375mg/m 2 1 Intravenous infusion in 1000ml sodium chloride 0.9% great team building activities onlineWeb20 de abr. de 2024 · HyperCVAD Alternating with High-Dose Methotrexate and Cytarabine + Rituximab 7,b,e,f Cycle A Days 1-3: Cyclophosphamide 300mg/m 2 IV over 3 hours … florian wannerWebIn this prospective study, we examined the toxicity and efficacy of an intensified conditioning regimen for treatment of patients with relapsed or high-risk acute lymphoblastic … florian wardemann