This article deals with protein targeting in eukaryotes unless specified otherwise. Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside the cell. Proteins can be targeted to the inner space of an organelle, different … See more In 1970, Günter Blobel conducted experiments on protein translocation across membranes. Blobel, then an assistant professor at Rockefeller University, built upon the work of his colleague See more Since the translation of mRNA into protein by a ribosome takes place within the cytosol, proteins destined for secretion or a specific organelle must be translocated. This process can … See more Protein transport is defective in the following genetic diseases: • Mohr–Tranebjaerg syndrome • Zellweger syndrome • Adrenoleukodystrophy See more • Minimotif Miner is a bioinformatics tool that searches protein sequence queries for a known protein targeting sequence motifs. See more Signal peptides serve as targeting signals, enabling cellular transport machinery to direct proteins to specific intracellular or extracellular locations. While no consensus sequence has been identified for signal peptides, many nonetheless possess a characteristic … See more Mitochondria While some proteins in the mitochondria originate from mitochondrial DNA within the organelle, most mitochondrial proteins are synthesized as See more As discussed above (see protein translocation), most prokaryotic membrane-bound and secretory proteins are targeted to the plasma membrane by either a co … See more Web17 Jan 2011 · Posttranslational modifications can take place in different cellular organelles such as the RER, Golgi, endosomes, lysosomes and secretory vesicles. The Golgi is …

Describe the post-translational sorting of proteins. What …

WebPost-translational sorting of proteins is a process that cells use to regulate the distribution of proteins in different cellular compartments. This... See full answer below. WebEmerging evidences suggest that post-translational modifications (PTMs) can regulate the sorting of specific proteins into EVs and such proteins with specific PTMs have also been … araraquara atibaia km

The Role of Post-Translational Modifications in Targeting Protein …

Web17 Jan 2011 · Abstract Polypeptides can be modified in the rough endoplasmic reticulum (RER) either during their synthesis (cotranslational) or after the initial synthesis has been … WebWith the many options for protein destinations, the rough ER is involved in co-translational sorting of the proteins containing certain signal sequences. Proteins destined for similar … WebThis is known as post-translational translocation. ADVERTISEMENTS: There are four mitochondrial locations where the proteins are targeted. These are outer membrane, inner … bakdb怎么打开